| 2005 | Khoo, K.M., Chang, C.F., Schubert, J., Wondrak, E.M., Chng, H.H. Expression and purification of the recombinant His-tagged GST-CD38 fusion protein using the baculovirus/insect cell expression system. Protein Expression & Purification 40, 396-403. |
| 2000 | Geselowitz, D.A., Cramer, H., Wondrak, E.M., Player, M.R. and Torrence, P.F. Fluorescence resonance energy transfer analysis of RNase L-catalyzed oligonucleotide cleavage. Antisense Nucleic Acid Drug Dev. 10, 45-51. |
| 1999 | Louis, J.M., Wondrak, E.M., Kimmel, A.R.,
Wingfield, P.T. and Nashed, N.T. Proteolytic Processing of HIV-1 Protease Precursor, Kinetics and Mechanism. J. Biol. Chem. 274, 23437-23442. |
| 1998 | Player, M.R., Wondrak, E.M., Bayly, S.F. and Torrence, P.F. Ribonuclease L, a 2-5A-Dependent Enzyme: Purification to Homogeneity and Assays for 2-5A Binding and Catalytic Activity. Methods 15, 243-253. |
| 1997 | Weber, I.T., Wu, J., Adomat, J., Harrison, R.W., Kimmel, A.R., Wondrak, E.M. and Louis, J.M. Crystallographic Analysis of Human Immunodeficiency Virus 1 Protease with an Analog of the Conserved CA-p2 Substrate -- Interactions with Frequently Occurring Glutamic Acid Residue at P2' Position of Substrates. Eur. J. Biochem. 249, 523-530. |
| 1996 | Wondrak, E.M. and Louis, J.M. Influence of Flanking Sequences on Dimer Stability of the Human Immunodeficiency Virus Type 1 Protease. Biochemistry 35, 12957-12962. |
| 1996 | Wondrak, E.M., Nashed, N.T., Haber, M.T., Jerina, D.M., and Louis, J.M. A Transient Precursor of the HIV-1 Protease: Isolation, Characterization and Kinetics of Maturation. J. Biol. Chem. 271, 4477-4481. |
| 1995 | Louis, J.M., Wondrak, E.M., and Nashed, N.T. Proteolytic Processing Mechanism of Human Immunodeficiency Virus. AIDS Res. Hum. Retroviruses 11s, S162. |
| 1994 | Wondrak, E.M., Kimmel, A.R., and Louis, J.M. Processing of the Mature HIV-1 Nucleocapsid Protein by the Viral Protease. J. Prot. Chem. 13, 543. |
| 1994 | Wondrak, E.M., Sakaguchi, K., Rice, W.G., Kun, E., Kimmel, A.R., and Louis, J.M. Removal of Zinc is Required for Processing of the Mature Nucleocapsid Protein of Human Immunodeficiency Virus, Type 1, by the Viral Protease. J. Biol. Chem. 269, 21948-21950. |
| 1993 | Wondrak, E.M., Louis, J.M., de Rocquigny, H., Chermann, J.C., and Roques, B.P. The gag Precursor Contains a Specific HIV-1 Protease Cleavage Site Between the NC (p7) and p1 Proteins. FEBS Lett. 333, 21-24. |
| 1993 | Camplo, M., Charvet, A.-S., Faury, P., Wondrak, E.M., Chermann, J.-C., and Kraus, J.-L. Synthesis and Antiviral Activity of a Potential Prodrug: N4-retinol 3'-thia-2',3'-dideoxycytidine. Med. Chem. Res. 3, 87-95. |
| 1991 | Louis, J.M., McDonald, R.A., Nashed, N.T., Wondrak, E.M., Jerina, D.M., Oroszlan, S., and Mora, P. Autoprocessing of the HIV-1 Protease Using Purified Wild-Type and Mutated Fusion Proteins Expressed at High Levels in Escherichia coli. Eur. J. Biochem. 199, 361-369. |
| 1991 | Tozser, J., Blaha, I., Copeland, T.D., Wondrak, E.M., and Oroszlan, S. Comparison of the HIV-1 and HIV-2 Proteinases Using Oligopeptide Substrates Representing Cleavage Sites in gag and gag-pol Polyproteins. FEBS Lett. 281, 77-80. |
| 1991 | Wondrak, E.M., Louis, J.M., Mora, P.T., and Oroszlan, S. Purification of the HIV-1 Wild-Type Protease and Characterization of Proteolytically Inactive HIV-1 Protease Mutants By Pepstatin A Chromatography. FEBS Lett. 280, 347-350. |
| 1991 | Wondrak, E.M., Louis, J.M., and Oroszlan, S. The Effect of Salt on the Michaelis Menten Constant of the HIV-1 Protease Correlates with the Hofmeister Series. FEBS Lett. 280, 344-346. |
| 1991 | Tozser, J., Gustchina A., Weber, I.T., Blaha, I., Wondrak, E.M., and Oroszlan, S. Studies on the Role of the S4 Substrate Binding Site of HIV Proteases. FEBS Lett. 279, 356-360. |
| 1990 | Wondrak, E.M., Copeland, T.D., Louis, J.M., and Oroszlan, S. A Solid Phase Assay for the Protease of the Human Immunodeficiency Virus. Anal. Biochem. 188, 82-85. |
| 1990 | Grobelny, D., Wondrak, E.M., Galardy, R.E., and Oroszlan, S. Selective Phosphinate Transition State Analogue Inhibitors of the Human Immunodeficiency Virus. Biochem. Biophys. Res. Commun. 169, 1111-1116. |
| 1990 | Copeland, T.D., Wondrak, E.M., Tozser, J., Roberts, M.M., and Oroszlan, S. Substitution of Proline with Pipecolic Acid at the Scissile Bond Converts a Peptide Substrate of HIV Proteinase into a Selective Inhibitor. Biochem. Biopphys. Res. Commun. 169, 310-314. |
| 1989 | Louis, J.M., Wondrak, E.M., Smith, C.A.D., Mora, P.T., and Oroszlan, S. E.coli expressed HIV-1 Protease Mutants Containing Arg87/Asn88 Substitutions are Inactive. In: Curr. Comm. Mol. Biol. - Viral Proteinases as Targets for Chemotherapy. H. Krausslich, S. Oroszlan and E. Wimmer (eds). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, pp. 161-167. |
| 1989 | Louis, J.M., Smith, C.A.D., Wondrak, E.M., Mora, P.T., and Oroszlan, S. Substitution Mutations of the Highly Conserved Arginine 87 of HIV-1 Protease Results in Loss of Proteolytic Activity. Biochem. Biophys. Res. Commun. 164, 30-38. |
| 1989 | Nashed, N.T., Louis, J.M., Sayer, J.M., Wondrak, E.M., Mora, P., Oroszlan, S., and Jerina, D.M. Continuous Spectrophotometric Assay for Retroviral Proteases of HIV-1 and AMV. Biochem. Biophys. Res. Commun. 163, 1079-1085. |
| 1989 | Louis, J.M., Wondrak, E.M., Copeland, T.D., Smith, C.A.D., Mora, P.T., and Oroszlan, S. Chemical Synthesis and Expression of the HIV-1 Protease in E. coli. Biochem. Biophys. Res. Commun. 159, 87-94. |
| 1988 | Wondrak, E.M., Löwer, J., and Kurth, R. Inhibition of HIV-1 RNA Dependent DNA Polymerase and Cellular Polymerases alpha, beta and gamma by Phosphono ormic Acid and Other Drugs. Chemical Abstracts 21, 23. |
| 1988 | Wondrak, E.M., Löwer, J., and Kurth, R. Inhibition of HIV-1 RNA Dependent DNA Polymerase and Cellular Polymerases alpha, beta and gamma by Phosphono Formic Acid and Other Drugs. J. Antimicrob. Chemothera. 21, 151-161. |
| 1987 | Wondrak, E.M., Behr, E., Löwer, J., and Kurth, R. Wirkung von Foscarnet-Derivaten auf die enzymatische Aktivität der Reversen Transkriptase von HIV-1 und der zellulären DNS Polymerasen alpha, beta und gamma. In: AIDS, Statusseminar des Bundesministeriums für Forschung und Technologie, Bonn-Bad Godesberg, September 1987, W. Vettermann und M. Schauzu (eds). Berlin: Bundesgesundheitsamt, pp. 321-332. |
| 1987 | Löwer, J., Wondrak, E.M., and Kurth, R. Genome Analysis and Reverse Transcriptase Activity of Human Teratocarcinoma-derived Retrovirus. J. gen. Virol. 68, 2807-2815. |
| 1986 | Wondrak, E.M., Löwer, J., and Kurth, R. Functional Purification and Enzymatic Characterization of RNA Dependent DNA Polymerase of HIV. J. gen. Virol. 67, 2791-2797. |
| 1986 | Werner, A., Wondrak, E.M., and Kurth, R. Ansätze zur Chemotherapie und Immunprophylaxe (Impfung) der LAV/HTLV-III Infektionen. In: AIDS II, Jahrestagung der Deutschen Gesellschaft für Infektiologie, Mai 1986, E.B. Helm, W. Stille und E. Vanek (eds). München: Zuckschwertverlag, pp. 207-213. |
| 1986 | Kurth, R., Wondrak, E.M., and Löwer, J. Aspekte der Chemotherapie von LAV/HTLV-III-Infektionen. In: Prophylaxe und Therapie der Viruserkrankungen. Bericht von der Tagung der Deutschen Vereinigung zur Bekämpfung der Viruserkrankungen e.V., München 1986, F. Deinhardt und H. Spiess (eds). Marburg/Lahn: Die Medizinische Verlagsgesellschaft mbH, pp. 80-88. |